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What Causes Lipedema?

Doctors don’t yet know the exact cause of lipedema, but there is a hereditary component. Typically the women in a family may tend to carry their weight in their hips and thighs. Any major hormonal shift throughout different life stages can trigger or increase the effect of lipedema. Some examples of this would be puberty, which is a very common trigger and usually the first one. Another would be pregnancy, then menopause. All of these cause a change in hormonal balance, which is related to the onset of lipedema. It seems to occur in relation to estrogen levels, so this is why it affects women more than it does men.